WSEAS Transactions on Biology and Biomedicine
Print ISSN: 1109-9518, E-ISSN: 2224-2902
Volume 12, 2015
Graphical Representation and Comparison of Whole Genome Sequences of Different Strains of Mycobacterium Tuberculosis
Authors: ,
Abstract: Tuberculosis (TB) is global health problem and is the leading cause of mortality. Global TB control is a difficult task due to the prevalence of multidrug resistant (MDR) and extensively drug resistant (XDR) strains of TB. New tools for faster and accurate diagnosis of drug-resistant TB are urgently needed as early detection of drug resistance allows starting of an appropriate treatment. Need for faster assessment can be addressed by genomic signal processing based methods. In this paper, a graphical method has been used to compare the DNA(deoxyribonucleic acid) sequences of different strains of tuberculosis that predict the nature of the mycobacterium tuberculosis (MTB) strains thus saving time for initiating adequate therapy.
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Keywords: Tuberculosis, Extensive Drug Resistant (XDR), Multidrug Resistant (MDR), Drug susceptible (DS), Genomic Signal Processing, Z-curves, graphical representations
Pages: 1-7
WSEAS Transactions on Biology and Biomedicine, ISSN / E-ISSN: 1109-9518 / 2224-2902, Volume 12, 2015, Art. #1