86cbbef7-1c9d-4943-bc04-9aa9ab1ce88b20210806023955399wseas:wseasmdt@crossref.orgMDT DepositWSEAS TRANSACTIONS ON ENVIRONMENT AND DEVELOPMENT2224-34961790-507910.37394/232015http://wseas.org/wseas/cms.action?id=40311820211820211710.37394/232015.2021.17https://wseas.org/cms.action?id=23258OlhaPopeloDepartment of Management and Civil Service, Chernihiv Polytechnic National University, Chernihiv, UKRAINESvitlanaTulchynskaDepartment of Economics and Entrepreneurship, National Technical University of Ukraine, “Igor Sikorsky Kyiv Polytechnic Institute”, Kyiv, UKRAINEOlgaGarafonovaDepartment of Management, Kyiv National Economics University named after Vadym Hetman, Kyiv, UKRAINELiubovKovalskaDepartment of Entrepreneurship, Trade and Logistics, Lutsk National Technical University, Lutsk, UKRAINESemenKhaninDepartment of Management and Public Administration, IHE “Academician Yuriy Bugay International Scientific and Technical University”, Kyiv, UKRAINEModern globalization processes of economic development are increasingly focusing on the regional level of economic development. The regional economic systems are the basis of economic development, as evidenced by the practice of European countries. Innovative orientation is and remains important for creative economy development, because it is the innovative development of regional economic systems that allows to increase efficiency of the economic activity, to use available resources more rationally without harming the environment, to improve living standards and more. In turn, innovative orientation of economic development of regional economic systems requires the development of methodological approaches to assess the regional innovation efficiency. The outlined and others determined the relevance of the scientific research on the development of a methodological approach to assessing innovative development efficiency of regional economic systems, to which this article is devoted. As a result of the research, a methodical approach to assessing the dynamics of innovation efficiency of regional economic systems in the conditions of the creative economy development, which provides for four stages of its implementation, was developed. This approach allows to objectively analyze innovation efficiency of regions by determining the integrated index of innovation efficiency and the coefficient of the innovation efficiency dynamics, as well as to determine the most influential indicators that will further develop mechanisms to enhance innovation processes in regional economic systems and to increase their innovative development efficiency. The proposed methodological approach to assessing innovative development efficiency of Polish voivodeships has been tested.77202177202168569566https://wseas.com/journals/ead/2021/b345115-664.pdf10.37394/232015.2021.17.66https://wseas.com/journals/ead/2021/b345115-664.pdf10.1007/s40309-016-0086-0Aminova, E. (2016). 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